Mon premier blog

Pharmacokinetic-pharmacodynamic modeling and simulation Peter L Bonate, SpringerLink
Publisher: Springer

Pharmacokinetic-Pharmacodynamic Modeling and Simulation By Peter Bonate Publisher: Springer Number Of Pages: 387. Mechanistic within-host models relating blood anti-malarial drug concentrations with the parasite-time profile help in assessing dosing schedules and partner drugs for new anti-malarial treatments. Toufigh Gordi, President of PK/PD and Clinical Pharmacology Services, will present a talk at the 4th World PK/PD Summit on November 28, 2012, in Frankfort, Germany. Part of these questions may be addressed through simulations from pharmacokinetic (PK) and pharmacodynamic (PD) models of HU. Cognigen Corporation provides strategic pharmacology and pharmacometric consulting services, PK/PD model development with NONMEM, clinical trial simulations, exposure-response evaluations, dose justification strategies and The 3-day workshop will be preceded by Pharmacokinetic–Pharmacodynamic Modeling: Concepts and Applications, a workshop presented by William J. A comprehensive simulation study to assess the utility of a stage-specific pharmacokinetic-pharmacodynamic (PK-PD) model for predicting within-host parasite response was performed. LLC, a drug development advisory firm with expertise in drug-disease modeling and simulation, today announced that Dr. Bonate, "Pharmacokinetic-Pharmacodynamic Modeling and Simulation" Sp ger | 2011 | ISBN: 144199484X | 651 pages | PDF | 11,1 MB. A natural hierarchy exists in pharmacokinetic-pharmacodynamic modeling culminating in population pharmacokinetic models, which are a specific type of nonlinear mixed effects model. Pharmacokinetic-Pharmacodynamic Modeling and Simulation. Gordi will describe various models, including pharmacokinetic models, mechanistic pharmacodynamics models, and systems pharmacology models.